Liver Health Product Buyer’s Guide (updated July 2024)

How To Find A High Quality Liver Support Supplement That Really Works!

An image of the site's  Senior Editor - Sally Harper.
  Sally Harper
  Senior Editor
  Health & Wellness Advice

A good quality liver support supplement can significantly protect the liver as well as improve general health. The powerful properties found in many natural ingredients provide not only direct benefits for taking care of your liver, but also have knock-on effects on the whole body for an overall sense of well-being and vitality. Our research has shown that given the correct dosage and potency of specific key ingredients – you can achieve incredible results. 

Many people who suffer from liver-related diseases choose to improve their symptoms by taking a liver support supplement, which has been shown in studies to provide numerous health benefits. The more specific ones include protecting the liver cells from inflammation, encouraging the production of bile, and detoxifying the liver, but they can also help to increase cardiovascular health, decrease joint inflammation, boost cognitive function, and strengthen antioxidant defenses.

Looking for a liver support supplement doesn’t have to be confusing or intimidating. With our professional knowledge to guide you through the market, you’ll be able to tell which supplements are worth buying and which you should stay away from. We’ve researched the market and thoroughly examined the products available to create a helpful guide that will lead you to the right liver support supplement for you. This guide will advise you on what to look for, explain how liver health supplements work, and even suggest some of our top picks.

5 Things To Look For In An Effective Liver Support Supplement

Every liver support supplement should contain:

  • both Milk Thistle and Artichoke, two of the most well-researched plants to treat liver disease and promote healthy liver function.
  • at least 100mg of Choline for optimal prevention of liver damage.
  • Glutathione, an antioxidant to help prevent liver cell death.
  • a bioavailability enhancer for faster, superior nutrient absorption.
  • non-GMO and cGMP certification to demonstrate purity and safety.

What We Uncovered

With a little research, we were able to spot the supplements from suppliers who were simply out to cash in on the latest trend versus those with products that we consider to be of high-quality.

  1. In short, many liver support supplements are not based on science and clinical research. Many do not use the correct ingredients or the exact dosages that have been clinically shown to produce results.
  2. What’s more, they are not 100% certified for purity and often include unnecessary ingredients that provide no benefit whatsoever. Some supplements do not contain the same potency as they claim on their labels, with many companies even hiding their supplement facts to prevent consumers from better understanding what is contained in the formulas.

Some companies think that sticking a label on their bottle with the words ‘Liver Support Supplement’, without even stating exactly what is inside each capsule and why certain ingredients have been added or not, is enough for people to want to buy their products. Unfortunately, many consumers fall for this scheme and are later disappointed by a lack of results. Don’t become one of these disheartened shoppers; check the facts and read the labels before you buy. 

Our Research

Our research identified key areas that we felt raised concerns when purchasing a liver support supplement. With so many products out there, we felt that we needed clear parameters as to what to look out for when investing in a liver support product.

  • Will it be effective? This is perhaps the main concern for consumers. After all, why waste your money on something that is useless? Unfortunately, there are many products that simply don’t work. Buyers should be aware that there is a precise science to creating an effective formula and that there are products that will work.
  • Will it be too expensive for me to purchase? Our research uncovered many manufacturers selling liver support capsules for $100 or more. People often think that by paying more they will get better quality, but this is not always the case. Don’t risk your hard-earned money on something that has an overinflated and unrealistic price. 
  • Is the company open and transparent? Manufacturers should be transparent and open, providing you with as much information and guidance as they can. For you to understand whether a company is simply exploiting the latest trends or not, you need to be consumer savvy in order to establish which are the best companies to purchase products from and which ones to avoid. 

Finding Effective, Quality Liver Support Supplements

There are several key elements to look out for that can pretty much guarantee a product’s authenticity:

  1. Monitoring By A Third Party: There are organizations that will independently monitor and track the reputation of a company and assess their customer satisfaction levels. A company’s reputation is incredibly important within the health industry. Make sure you select a top provider that has an impeccable reputation and is backed by an independent third-party monitoring organization.
  2. 100% Money-Back Guarantee: Many companies offer you a money-back guarantee if their products do not bring the results that you are looking for. Some are better than others. Choose a company that has a solid satisfaction guarantee. A strong guarantee demonstrates a manufacturer’s confidence that their product will deliver the desired results.
  3. External Testing: This is not the same as a monitoring company. Third-party testing substantiates and verifies the quality of the manufacturer’s product. It can be very expensive for manufacturers to undertake, and can even disqualify entire shipments of products that don’t reach the correct standards. That being said, when manufacturers don’t have independent quality control and testing, there is no way of knowing if their products are effective, or indeed, safe.

Our Research Results

An effective liver support supplement should contain top quality, clinically proven ingredients in significantly potent doses for optimal effect. There are certain quantities of specific herbs and nutrients that can increase a formula’s antiviral, antioxidant, and anti-inflammatory properties to help optimize the liver’s functions. 

We looked for the inclusion of Milk Thistle and Artichoke extracts. These ingredients are the most clinically researched genus of thistles and have been used for centuries for balancing liver health and treating liver-related ailments. We also looked for a high dose of Choline which plays an important role in removing fat and cholesterol from the liver, and Glutathione, an antioxidant to help with the prevention of liver cell death. Additionally, we looked for the inclusion of a bioavailability enhancer, such as BioPerine®, for increasing nutrient absorption and delivering faster results.

Most products failed to pass our specific criteria.

There are some manufacturers who fail their customers by adding unnecessary ingredients that weaken the potency of their products. Other manufacturers simply fail when they use a lower standardization than what has been proven effective in scientific studies. Others filled their capsules with binders, additives, or preservatives that could potentially be harmful. All but a few of them avoided quality control testing. Given our stringent parameters and reasons for choosing our top products, we are sure our top picks will help you achieve the results you are looking for.

Why Did We Select Liversyl As Our #1 Choice?

Our top pick not only met all of our strict criteria for a quality liver support supplement, but it also beat it!

Look at what it contains:

  • BioThistle™ Liposomal Milk Thistle – no others have this bioavailable blend. Includes 300mg Milk Thistle Extract, standardized to 80% Silymarin (the active ingredient).
  • 200mg Artichoke Extract in BioArtichoke™ – very few others have this high dosage.  
  • 50mg L-Glutathione (reduced) – an antioxidant to help prevent liver cell death, which could then result in fatty liver disease.
  • 125mg Choline – to help prevent fat and cholesterol buildup. Far more than the amount provided by most other formulas.
  • BioPerine® – for improving bioavailability and delivering quicker results 

Our Top Liver Support Product Choices

We think you will agree that our top choice stands above and beyond the competition. The company’s excellent reputation, top quality product, external independent monitoring and testing – coupled with an incredible money-back guarantee policy – makes this an undoubtedly solid pick for our #1 choice.

Liver Health Report

Rating: Excellent


Money Back Guarantee
Consumer Feedback
Company Reputation

Editor’s Choice

Approved Science Liversyl

If you are looking to encourage liver cell repair, boost a detox, support bile production and improve your overall liver health then Liversyl is something that deserves your undivided attention. Of all the liver support supplements currently available on the market, this is the one that deserves a closer look, and very likely, the one that will change your life for the better!

It contains the highest quality, clinically-proven natural ingredients for promoting liver health. It was the only product we found that contains ALL the key ingredients on our must-have list in one easy- to-use formula! It includes not one but two unique trademarked ingredients – BioThistle™, a blend of Milk Thistle Extract with phospholipids in a liposomal delivery system, and BioArtichoke™, a high dose of Artichoke Extract mixed with BioPerine® for enhanced bioavailability and quicker results. It also contains Choline and L-Glutathione for additional antioxidant and detoxification benefits. Furthermore, it does not contain any additives or preservatives and is 100% safe to use. Essentially, this product ticks all the right boxes for an effective liver support formula.

Quality: Liversyl contains high-grade, natural, clinically-verified ingredients that are GMP certified.

Reputation: Approved Science’s reputation is top quality. They are well known in the industry and are an established company that provides great customer support service, secure and easy checkout as well as prompt, efficient delivery. This manufacturer has several third-party monitoring services, including buySAFE, Norton, and Trustee, as well as an A+ rating from the quality monitoring company QualityTrusted. Approved Science’s commitment to the health industry and consumers is excellent, providing further legitimacy to their products by producing them in an FDA-registered laboratory.

Money-Back Guarantee: Every item sold is supported by a 60-day 100% money-back guarantee. Such guarantees from manufacturers show strong confidence in their products’ ability to deliver results. Great news for consumers.

Bottom Line: If you are looking for a product that ticks all the boxes for an effective liver support supplement that comes from an established reputable company with an excellent money-back guarantee, then this is the supplement for you.

It would be good to note that, due to high demand, Approved Science Liversyl is often sold out. To avoid having to back order, don’t hesitate to make that purchase when you see it in stock.

See The Full Review


Rating: Good



Vital Nutrients Liver Support

Promoted as a health product to support liver function, help inhibit arachidonic acid metabolism, and protect liver cells against damage, Vital Nutrients Liver Support is our next product up for review. This product is from an established American company with over two hundred dietary supplements and lots of good product reviews, but is that enough to make us think that this is a successful product? 

This product includes some of the ingredients that we were specifically looking for in a liver support supplement. Its formula contains Artichoke Extract, Milk Thistle Extract and Choline (Bitartrate) in addition to other active herbs and compounds for supporting liver health. As far as formulas go, this one looks promising. However, it is unclear to us if this formula will actually be effective.  Although the ingredients are pure and high quality, some of them are not in the proven clinical doses, and there is no addition of a bioavailability enhancer such as BioPerine® which will affect the overall effectiveness of this product.

Vital Nutrients supplements are third-party tested, free of unnecessary ingredients and contaminants and have a 30-day return policy. These are all things that endorse a product, even though the return policy is shorter and less comprehensive than some of its peers. When reviewing this product, we found a few things that just didn’t meet our standards. Read our full review before you buy for a thorough list of pros and cons regarding Vital Nutrients Liver Support.

Click here to read the full review


Rating: OK


Body Ecology LivAmend

LivAmend claims to be an effective supplement for supporting the liver, increasing bile flow and helping with bowel elimination. It is one of an extensive range of products from Body Ecology, a whole-body healing approach from Donna Gates that focuses on immune disorders and digestive health, and aims to restore health and vitality via supplements, dietary changes, courses and educational materials.

When reviewing this product, we were pleased to see an ingredient list that is at least partially based on science and uses high doses of some of the active ingredients. The 430mg dose of Artichoke Extract is especially high, and more than the amount found in many brands, but 60mg of Milk Thistle Extract is not even a quarter of the amount found in our Editor’s Choice product. Unfortunately, there are no ingredients added to increase the bioavailability of the nutrients to achieve faster results, which also reduces the overall benefits of this product. 

We think Body Ecology did a reasonably good job in crafting their formula, especially considering that there are no harmful additives, fillers, binders or artificial ingredients. LivAmend does have cGMP certification, but there is no indication of testing done on either the ingredients or the finished product, nor any third-party testing. Additionally, there is only a partial money-back policy, with conditions attached to product returns. These are all elements that inspire customer confidence and could have helped to push this product higher up in the rankings. Continue reading to see why this product made our #3 spot

Click here to read the full review

What You’ll Discover:

Which liver support supplement is the BEST BUY and comes with a great GUARANTEE!
Which formula and ingredients are the most EFFECTIVE and work the fastest?
How NOT to get ripped off! BE AWARE of poor quality and cheap products.

Top 6 Items to Consider:

  1. Ingredients
  2. Cost Per Serving
  3. Product’s Testing Results
  4. Company’s Reputation
  5. Consumer Reviews
  6. Return Policy & Satisfaction Guarantee

Sign Up For Our Newsletter!

We will send the latest and most relevant information regarding liver support supplements straight to your inbox to keep you updated and informed.

Our promise: We will never share your contact details unless you give us permission. And we will only ever send you information that is helpful and significant.